The Silcoff Selections: NFL Week 11 Predictions – Straight Up & Against the Spread Picks

The Silcoff Selections are here for Week 11 of the 2025 NFL Season! Below are my records for my straight up and against the spread picks for the season thus far.

Records Last Week:

Straight Up: 8-6

Against The Spread: 6-8

Season Records:

Straight Up: 91-57-1

Against The Spread: 67-81-1

Thursday Night Football: New York Jets (2-7) @ New England Patriots (8-2) I Line: Patriots -13

The Patriots enter Week 11 red-hot, having won seven straight games, and they’re showing no signs of slowing down. Quarterback Drake Maye is playing at an MVP-caliber level, while Justin Fields and the Jets’ offense continue to struggle. New England’s defense has quietly become one of the better units in the league, and at home, they should roll. Expect a convincing Patriots win on Thursday night.

Score Prediction: Patriots 31, Jets 14

ATS Pick: Patriots -13

Early Sunday Slate: Commanders-Dolphins End 2025 International Series

Spain Game: Washington Commanders (3-7) @ Miami Dolphins (3-7) I Line: Dolphins -2.5

This matchup might not be worth setting your alarm for. Both teams are dealing with significant injuries — Jayden Daniels and Terry McLaurin are out for Washington. Miami, fresh off a massive upset win over the Bills, enters with momentum and better overall health. The Dolphins should handle business abroad.

Score Prediction: Dolphins 28, Commanders 21

ATS Pick: Dolphins -2.5

Los Angeles Chargers (7-3) @ Jacksonville Jaguars (5-4) I Line: Chargers -3

Despite dealing with offensive line injuries, the Chargers should win on the road. Justin Herbert remains one of the league’s elite quarterbacks, and Ladd McConkey is beginning to find his rhythm. Jacksonville’s receiving corps is banged up — Travis Hunter is out for the season, and Brian Thomas Jr. remains questionable — which gives Los Angeles the upper hand.

Score Prediction: Chargers 23, Jaguars 21

ATS Pick: Jaguars +3

Tampa Bay Buccaneers (6-3) @ Buffalo Bills (6-3) I Line: Bills -5.5

After being dominated by Miami, the Bills return home looking to bounce back. The Buccaneers put up a fight last week against New England but fell short. With Buffalo desperate to keep pace in the AFC East — especially if the Patriots win Thursday — expect Josh Allen and the Bills to respond with a win in front of their home crowd.

Score Prediction: Bills 27, Buccaneers 23

ATS Pick: Buccaneers +5.5

Chicago Bears (6-3) @ Minnesota Vikings (4-5) I Line: Vikings -3

This is a kitchen sink for Minnesota. I think the Vikings bounce back and get a much needed win at home to stay in the playoff picture.

Score Prediction: Vikings 24, Bears 20

ATS Pick: Bears +3

Green Bay Packers (5-3-1) @ New York Giants (2-8) I Line: Packers -7

The Packers are looking to rebound after a dismal offensive performance against the Eagles. With Jameis Winston expected to start for the Giants, Green Bay’s defense should be able to capitalize on mistakes. Expect Jordan Love and the Packers to get back on track with a road win.

Score Prediction: Packers 20, Giants 14

ATS Pick: Giants +7

Houston Texans (4-5) @ Tennessee Titans (1-8) I Line: Texans -6

Don’t look now — the Texans are back in the playoff mix. After starting 0-3, they’ve won four of their last six and sit at 4-5 entering Week 10. C.J. Stroud is expected to return, and Houston’s pass rush should wreak havoc on Cam Ward. While the Titans are coming off a bye, the Texans are simply the better team on both sides of the ball. Texans win on the road.

Score Prediction: Texans 21, Titans 13

ATS Pick: Texans -6

Carolina Panthers (5-5) @ Atlanta Falcons (3-6) I Line: Falcons -3.5

Despite returning from Germany without a bye week, the Falcons are favored. However, the Panthers often play them tough — and Bryce Young tends to perform best when expectations are low. Fatigue could play a factor for Atlanta, and Carolina has enough motivation to pull off the surprise. Panthers win a road upset.

Score Prediction: Panthers 23, Falcons 20

ATS Pick: Panthers +3.5

Cincinnati Bengals (3-6) @ Pittsburgh Steelers (5-4) I Line: Steelers -5.5

The Steelers looked lifeless on offense last week, but they now face one of the worst defenses in football. The Bengals, meanwhile, are still trying to stay afloat until Joe Burrow can return. While Cincinnati might keep it close, Pittsburgh’s defense should do enough to secure a narrow victory at home. Steelers win, Bengals cover.

Score Prediction: Steelers 30, Bengals 23

ATS Pick: Steelers -5.5

Late Sunday Slate: Seahawks-Rams Play In the Game of the Week

Seattle Seahawks (7-2) @ Los Angeles Rams (7-2) I Line: Rams -3

This is the marquee matchup of the weekend. Matthew Stafford is playing at an elite level, but Mike Macdonald’s Seahawks defense travels exceptionally well. Seattle’s defensive backfield could be the deciding factor, with Jaxon Smith-Njigba expected to exploit the Rams’ secondary. Add in Sam Darnold’s revenge motivation after last year’s playoff loss to the Rams, and the pick is clear: Seahawks win on the road.

Score Prediction: Seahawks 27, Rams 24

ATS Pick: Seahawks +3

San Francisco 49ers (6-4) @ Arizona Cardinals (3-6) I Line: 49ers -2.5

This game looked intriguing until Marvin Harrison Jr. underwent appendix surgery, sidelining him for the week. Without him, Jacoby Brissett and the Cardinals’ offense lack firepower beyond Trey McBride. The 49ers, coming off a divisional loss to the Rams, are desperate to stay alive in the playoff race. Expect a focused and dominant effort. 49ers win on the road.

Score Prediction: 49ers 24, Cardinals 20

ATS Pick: 49ers -2.5

Baltimore Ravens (4-5) @ Cleveland Browns (2-7) I Line: Ravens -7.5

This one could get ugly fast. The Ravens should dominate from start to finish, taking back control of the AFC North. Baltimore’s offense is clicking, and their defense should completely overwhelm Cleveland. Ravens win big.

Score Prediction: Ravens 23, Browns 16

ATS Pick: Browns +7.5

Kansas City Chiefs (5-4) @ Denver Broncos (7-2) I Line: Chiefs -4

If the Broncos pull off an upset here, the AFC West race could get chaotic — but it’s hard to see it happening. Denver’s offense looked dreadful against Las Vegas, and the Chiefs, fresh off a bye, should be ready. Andy Reid rarely loses in these situations. Chiefs stay in the division hunt with a road victory.

Score Prediction: Chiefs 23, Broncos 20

ATS Pick: Broncos +4

Sunday Night Football: Detroit Lions (6-3) @ Philadelphia Eagles (7-2) I Line: Eagles -2.5

Another potential NFC Championship preview. Both teams are banged up, but the Lions have shown resilience. Jahmyr Gibbs and Amon-Ra St. Brown should thrive, and Jared Goff will be well-protected behind one of the league’s best offensive lines. With extra rest compared to Philly, Detroit pulls off the upset win on the road.

Score Prediction: Lions 28, Eagles 24

ATS Pick: Lions +2.5

Monday Night Football: Dallas Cowboys (3-5-1) @ Las Vegas Raiders (2-7) I Line: Cowboys -3.5

This might not be a must-watch primetime game, but expect the Cowboys to cruise. Dak Prescott is playing at a high level, and even though Ashton Jeanty and Brock Bowers might make some plays, the Raiders can’t match Dallas’ overall talent. Cowboys win comfortably.

Score Prediction: Cowboys 33, Raiders 26

ATS Pick: Cowboys -3.5

Straight Up/Moneyline Picks:

• Patriots

• Dolphins

• Chargers

• Bills

• Vikings

• Packers

• Texans

• Panthers

• Steelers

• Seahawks

• 49ers

• Ravens

• Chiefs

• Lions

• Cowboys

Picks ATS:

• Patriots -13

• Dolphins -2.5

• Jaguars +3

• Buccaneers +5.5

• Vikings -3

• Giants +7

• Texans -7

• Panthers +3.5

• Steelers -5.5

• Seahawks +3

• 49ers -2.5

• Browns +7.5

• Broncos +4

• Lions +2.5

• COwboys -3.5