The Silcoff Selections: NFL Week 13 Predictions – Straight Up & Against the Spread Picks

The Silcoff Selections are here for Week 13 of the 2025 NFL Season! Below are my records for my straight up and against the spread picks for the season thus far.

Records Last Week:

Straight Up: 11-3

Against The Spread: 5-8-1

Season Records:

Straight Up: 112-65-1

Against The Spread: 81-93-4

Thanksgiving Game #1: Green Bay Packers (7-3-1) @ Detroit Lions (7-4) I Line: Lions -3

On paper, the Packers look like the better and healthier team heading into Thanksgiving—outside of running back Josh Jacobs.

But I don’t see Detroit getting swept by Green Bay after the embarrassing season-opening loss in Week 1. The Lions were fortunate to escape with a win last week against the Giants, largely due to Jahmyr Gibbs three-touchdown performance. That close call likely served as a wake-up call for the rest of the team, especially with their division hopes slipping.

If Detroit loses this game, the NFC North is essentially out of reach. They’re the more desperate team, and even though I think Green Bay will probably go deeper in the playoffs overall, I’m taking the Lions to win at home on Thanksgiving and avoid the sweep.

Score Prediction: Lions 27, Packers 23

ATS Pick: Lions -3

Thanksgiving Game #2: Kansas City Chiefs (6-5) @ Dallas Cowboys (5-5-1) I Line: Chiefs -3

For most of the week, I expected to pick Kansas City in this matchup—and realistically, I still probably should. Both teams are coming off dramatic comeback wins: the Chiefs erased an 11-point deficit against the Colts, while Dallas overcame a massive 21-0 hole against the Eagles.

The Cowboys’ defense has been shaky for much of the year, but since the acquisition of Quinnen Williams, the defensive line has improved significantly. That matters because the Chiefs’ offensive line hasn’t performed well, and I haven’t loved what I’ve seen from Kansas City’s offense recently.

Dak Prescott is playing some of the best football of his career and with CeeDee Lamb and George Pickens facing a suspect (though improving) Chiefs defense. I think Dallas pulls off the upset and steals this game to climb back into the playoff race.

Score Prediction: Cowboys 28, Chiefs 26

ATS Pick: Cowboys +3

Thanksgiving Game #3: Cincinnati Bengals (3-8) @ Baltimore Ravens (6-5) I Line: Ravens -7

Joe Burrow deserves respect for returning at 3–8 after missing so much time with injuries throughout his career. His competitive drive is unquestioned—but I don’t think it's going to matter here.

The Bengals look like a team that has mentally checked out of the season, even with Burrow back. Meanwhile, the Ravens haven't been playing their best football, but they’re still the stronger, more complete team. I expect a close contest early, but Baltimore should pull away late and secure the win at home.

Score Prediction: Ravens 31, Bengals 21

ATS Pick: Ravens -7

Black Friday Game: Chicago Bears (8-3) @ Philadelphia Eagles (8-3) I Line: Eagles -7

The Chicago Bears aren’t playing great football, but they are playing winning football. Philadelphia, meanwhile, is coming off a brutal collapse against the Cowboys.

This game has massive implications. If the Bears go into Philly and win, they legitimize themselves as true NFC contenders and possibly the NFC North favourites.

I think Chicago can keep this game close—maybe even leading in the second half—but the Eagles are a more talented roster. If they lose, it could resemble their late-season collapse from two years ago. In a field-goal-type game (as most Bears games have been), I’m taking the Eagles to win narrowly at home.

Score Prediction: Eagles 23, Bears 20

ATS Pick: Bears +7

Sunday Games

Arizona Cardinals (3-8) @ Tampa Bay Buccaneers (6-5) I Line: Buccaneers -2.5

Baker Mayfield’s status is uncertain. If he doesn’t play, I'd lean Cardinals. But assuming he fights through the injury—which he’s done throughout his career—I’ll take the Buccaneers in a close one.

Score Prediction: Buccaneers 24, Cardinals 20

ATS Pick: Buccaneers -2.5

Atlanta Falcons (4-7) @ New York Jets (2-9) I Line: Falcons -2.5

If Drake London is out, I like the Jets at home. Tyrod Taylor brings more to the offense than Justin Fields has all season, and I don’t trust Kirk Cousins. It’s a mild upset pick on paper, but I’m taking New York.

Score Prediction: Jets 17, Falcons 14

ATS Pick: Jets +3

Houston Texans (5-5) @ Indianapolis Colts (8-3) I Line: Colts -4

Houston looked great on Thursday Night Football, and the Colts blew it last week against the Chiefs. That makes this a tempting game to bet against Indianapolis.

The wild card here is C.J. Stroud’s status. If I knew Stroud was playing, I’d lean heavily toward Houston. But given the uncertainty—and the likelihood that the public will overreact to last week’s results—I’m taking the Colts at home. Jonathan Taylor should bounce back after being shut down by Kansas City, and Indy badly needs this divisional win.

Score Prediction: Colts 22, Texans 17

ATS Pick: Colts -4

Jacksonville Jaguars (7-4) @ Tennessee Titans (1-10) I Line: Jaguars -6.5

This is my upset pick. I think Tennessee wins at home.

The Jaguars consistently play with their food. Trevor Lawrence turned the ball over four times last week against the Cardinals, and two weeks before that, they blew a fourth-quarter lead to the Texans and Davis Mills.

Cam Ward looked comfortable and played well against the Seahawks last week, and I don’t see Tennessee going 1–16 this season. This division game feels like a perfect trap spot for Jacksonville, so I'm taking the Titans at home.

Score Prediction: Titans 24, Jaguars 17

ATS Pick: Titans +6.5

Los Angeles Rams (9-2) @ Carolina Panthers (6-6) I Line: Rams -10.5

Right now, the Rams are playing like the best team in football. Bryce Young struggled heavily against San Francisco, and while I don’t expect a blowout, the Rams should win comfortably.

Carolina may cover the 10.5-point spread, though. Teams embarrassed on Monday Night Football often rebound the following week, and no team is ever as good or as bad as they appeared in primetime. Still, the Rams take the win.

Score Prediction: Rams 30, Panthers 20

ATS Pick: Panthers +10.5

New Orleans Saints (2-9) @ Miami Dolphins (4-7) I Line: Dolphins -5.5

Two struggling teams, but Miami is coming off the bye while New Orleans looked awful last week against Atlanta. There isn’t much more to say: give me the Dolphins.

Score Prediction: Dolphins 27, Saints 16

ATS Pick: Dolphins -5.5

San Francisco 49ers (8-4) @ Cleveland Browns (3-8) I Line: 49ers -5

Shedeur Sanders gets another start, while Brock Purdy enters the week after a disastrous Monday Night Football outing that included three first-half interceptions despite the 49ers still getting the win. And with Cleveland’s defense being among the best in football, they can absolutely give him trouble.

Still, San Francisco is healthier and simply the better team. Kyle Shanahan should be able to scheme Purdy back on track, and although Myles Garrett may single-handedly keep the Browns competitive, I’m taking the 49ers on the road in a close game.

Score Prediction: 49ers 20, Browns 16

ATS Pick: Browns +5

Minnesota Vikings (4-7) @ Seattle Seahawks (8-3) I Line: Seahawks -11.5

Sam Darnold faces his former team—the one where he reinvented himself into a Pro Bowl-caliber quarterback last season. With J.J. McCarthy out due to a concussion, Max Brosmer likely gets the start for Minnesota.

I’m taking Seattle at home. The defense should bounce back after a mediocre showing against Tennessee. The Seahawks get the win.

Score Prediction: Seahawks 34, Vikings 17

ATS Pick: Seahawks -11.5

Las Vegas Raiders (2-9) @ Los Angeles Chargers (7-4) I Line: Chargers -9.5

The Raiders aren’t good. The Chargers are coming off a bye. Simple: Los Angeles wins.

Score Prediction: Chargers 28, Raiders 13

ATS Pick: Chargers -9.5

Buffalo Bills (7-4) @ Pittsburgh Steelers (6-5) I Line: Bills -3

It appears Aaron Rodgers will play, and the Steelers desperately need the win, especially if Baltimore wins on Thanksgiving.

But the Bills really need this game. I put their chances of winning the division maybe around 15%, and a loss would essentially eliminate them. I think Buffalo bounces back from last week’s ugly Thursday performance and wins on the road—though I wouldn’t be shocked if Pittsburgh pulls off the upset.

Score Prediction: Bills 27, Steelers 23

ATS Pick: Bills -3

Sunday Night Football: Denver Broncos (9-2) @ Washington Commanders (3-8) I Line: Broncos -5.5

Even if Jayden Daniels returns, it doesn’t change much. Denver is a significantly better team with one of the top defenses in the NFL. After upsetting the Chiefs two weeks ago and now coming off their bye, they should be well-prepared. Give me the Broncos on the road.

Score Prediction: Broncos 29, Commanders 17

ATS Pick: Broncos -6.5

Monday Night Football: New York Giants (2-10) @ New England Patriots (10-2) I Line: Patriots -7.5

I’m tempted to pick the upset here. With Will Campbell and Jared Wilson out, New England’s offensive line is banged up, and that opens the door for the Giants.

But the Giants are simply too unreliable. They frequently blow double-digit leads, and even with Jaxson Dart returning, it’s hard to trust them—especially in a primetime road game.

So while I have the Patriots on upset watch, I ultimately think Drake Maye and the Patriots handle business, move to 11–2, and head into their bye week in control of the AFC East.

Score Prediction: Patriots 28, Giants 19

ATS Pick: Patriots -7.5

Straight Up/Moneyline Picks:

• Lions

• Cowboys

• Ravens

• Eagles

• Buccaneers

• Jets

• Colts

• Titans

• Rams

• Dolphins

• 49ers

• Seahawks

• Bills

• Chargers

• Broncos

• Patriots

Picks ATS:

• Lions -3

• Cowboys +3

• Ravens -7

• Bears +7

• Buccaneers -2.5

• Jets +2.5

• Colts -4

• Titans +6.5

• Panthers +10.5

• Dolphins -5.5

• Browns +5

• Seahawks -11.5

• Bills -3

• Chargers -9.5

• Broncos -5.5

• Patriots -7.5